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KMID : 0861019980130020077
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Korea Journal of Herbology
1998 Volume.13 No. 2 p.77 ~ p.89
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Studies on the Antiallergic Reactions of the Herba Houttuyniae Extract
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盧柄圭/Rho, Byung Kyu
辛民敎/宋昊埈/Shin, Min Kyo/Song, Ho Joon
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Abstract
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This paper has presented the inhibitory activity of Herba Houttuyniae (HH) by using PCA reactions, Compound 48/80 and Substance P from rat peritoneal mast cells, and the effect on the inhibitory of the release of IgE in the spleen whole cells and U266B1.
The major results of our experiment on the inhibitory activity of HH are as follows.
1. HH remarkably inhibited the passive cutaneous anaphylaxis reaction upon the high density.
2. HH restrained type I allergic reactions as anaphylactic shocks caused by the injection Compound 48/80 inside the abdominal cavity.
3. This result suggests that HH inhibited histamine release in serum activated by Compound 48/80.
4. HH inhibited the histamine release induced by Compound 48/80 and Substance P in the rat peritoneal mast cells.
5. HH also exposed the dose-dependent inhibitory on the release of IgE by the LPS and LPS+IL-4 in the mouse spleen whole cells and human myeloma U266B1.
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